projects

 Ongoing projects and grants in the LOG:

• Functional characterization of germline CHEK2 variants (Petra Kleiblova, Zdenek Kleibl, in co-operation with Libor Macurek lab (IMG ASCR) and ENIGMA consortium).
• Identification of hypomorphic germline TP53 variants ((Petra Kleiblova, Zdenek Kleibl, in co-operation with Libor Macurek lab (IMG ASCR).
• RNA analysis as a tool for germline variant classification (Petra Kleiblova)
• Analysis of PRS in cancer patients (Marketa Janatova)
• Hereditary ovarian cancer (Jana Soukupova)
• Participation of LOG in the National Institute for Cancer Research (NICR)