Center of Oncocytogenetics

Center of Oncocytogenetics which is part of the Institute of Medical Biochemistry and Laboratory Diagnostics is the biggest facility in Czech Republic which is specialized in cytogenetics of malignant tumors. Together with Cytogenetic laboratory of Institute of Hematology and Blood Transfusion the examinations of blood, bone marrow cells and solid tumor cells are done and classical cytogenetic and molecular genetic methods are routinely used. There are performed fluorescence in situ hybridization (FISH), multicolor FISH (mFISH), multicolor banding FISH with high resolution (mBAND), array comparative genomic hybridization (aCGH), single nucleotide polymorphism array (SNP array) for routine laboratory check up and for research purposes as well. All necessary equipment is present in the laboratories: Zeiss fluorescence microscopes, Zeiss light microscopes equipped with computerized image analyses (MetaSystems), automat for harvesting cells for cytogenetic purposes, automatic cell dropper for cytogenetic preparations, automat for staining and restaining of microscopic slides with chromosomes. Automatic metaphase finder (Metafer) can during the working day search for metaphases and nuclei on eight microscopic slides at one experiment and record the positions of pathological cells.


In the Center of Oncocytogenetics samples from patients with preleukemia and leukemia from whole Prague and surroundings are examined. Except this routine work the research is performed with support of grant agencies GACR, IGA MZCR and international grant COST in the laboratories and technicians and scientific workers are involved in pregradual and postgradual teaching as well.

10.12.2012  |     |   zpět na Centre of cytogenetics