Central Hematology Laboratory
The Central hematologic laboratory also included Reference laboratory for automation in hematology Ministry of Health, which is already more than 20 years participated in the introduction of new technologies in the field. Central haematological laboratories today have special laboratory equipment. These are mainly blood count analyzers UniCel DxH 800 Beckman Coulter, Sysmex XE5000, coagulation analyzers BCS XP, Siemens and Sysmex CA 7000 Siemens ACL TOP companies Instrumentation Laboratory and apparatus for examination of primary hemostasis. The quality of work documents and accreditation according to DIN EN ISO 15189 for the following tests: Determination of blood counts with 5 - population differential, differential leukocyte budget in peripheral blood smear and bone marrow and reticulocytes in the peripheral blood smear. Determination of prothrombin time, activated partial thromboplastin time, fibrinogen according to Clauss, thrombin time, antithrombin III, D-dimer determination, reptilázového time, protein C, protein S, factors II, V, VII, X, VIII, IX, XI, XII, transferrin, alpha 2 macroglobulin, alpha 1 acid glykoproten, alpha 1 antitrypsin, C reactive protein (CRP), lupus anticoagulant, anti Xa inhibition units, von Willebrand factor antigen, and PICT - Determination of the inhibition of anti-Xa units. The laboratory is also accredited for molecular genetic methods - examinations of mutations in the gene for factor V - FV Leiden 1691 G / A by real-time PCR and mutation in the gene for prothrombin (factor II) 20210G / A. Meets the conditions as "Special requirements for quality and competence" of Act No. 373/2011 Coll, § 28, for genetic testing. The laboratory is also accredited by flow cytometry for determination of lymphocyte subpopulations in peripheral blood by flow cytometry, which is mainly specialized in the diagnosis of malignant lymphoma. There were solved several grant studies and in particular research plan č.64165 Ministry of Health: Diagnosis and treatment of genetic disorders.
