Témata PGS

Témata PGS se týkají širokého spektra expertiz a grantových projektů řešených na ÚLBLD. Aktuální nabízená témata pro akademický rok 2026/2027 (oborová rada - subject board; SB):

Dvořák Aleš, RNDr., Ph.D. (SB biochemistry and pathobiochemistry)

• TBD

 

Janatová Markéta, RNDr., Ph.D. (SB biochemistry and pathobiochemistry, SB biology and genetics)

• Identification of genetic factors predisposing to the development of various solid tumors in adults in the Czech population using next-generation sequencing (NGS)
• Analysis of the frequency of low-penetrance alleles associated with cancer development in the population, determination of their cooperative effect in the form of a polygenic risk score (PRS) for selected cancers, and evaluation of the clinical usefulness of the PRS for risk stratification of these diseases

 

Kalousová Marta, prof. MUDr., Ph.D. (SB Biochemistry and Pathobiochemistry)

• New biochemical and/or molecular genetic biomarkers in selected pathological states

 

Kleibl Zdeněk, prof. MUDr., Ph.D. (SB biochemistry and pathobiochemistry, SB biology and genetics)

• Analysis of hereditary cancer predisposition using multi-omics approaches
• Bioinformatic approaches for identifying germline and somatic genetic alterations underlying adult cancers
• Extracellular nucleic acids for the early detection of tumors in high-risk individuals

 

Kleiblová Petra, doc. MUDr, Ph.D. (SB biochemistry and pathobiochemistry, SB biology and genetics)

• NGS RNA analysis – characterization of tissue-specific alternative and aberrant splicing and its role in cancer predisposition

 

Lahoda Brodská Helena, doc. MUDr., Ph.D. (SB Biochemistry and Pathobiochemistry)

• Evaluation of current and new biomarkers in antimicrobial stewardship, possibility of managing antibiotic therapy using new markers (ATB guide)

 

Leníček Martin, MUDr., Ph.D. (SB Biochemistry and Pathobiochemistry)

• The Role of Bile Acids in Gastrointestinal Diseases

 

Muchová Lucie, doc. MUDr., Ph.D. (SB Biochemistry and Pathobiochemistry)

• Biological effects of the products of the heme catabolic pathway.

 

Pláteník Jan, MUDr., Ph.D. (SB Biochemistry and Pathobiochemistry)

• TBD

 

Soukupová Jana, RNDr., Ph.D. (SB biochemistry and pathobiochemistry, SB biology and genetics)

• Analysis of hereditary cancer predisposition using next gen sequencing (monogenic, polygenic, immunogenetic)

 

Springer Drahomíra, doc. Ing., Ph.D. (SB Biochemistry and Pathobiochemistry)

• TBD

 

Vítek Libor, prof. MUDr., Ph.D. (SB Biochemistry and Pathobiochemistry)

• TBD

 

Zemanová Zuzana, doc. RNDr., CSc. (SB Biochemistry and Pathobiochemistry)

• TBD

 

Zima Tomáš, prof. MUDr., DrSc., MBA (SB Biochemistry and Pathobiochemistry)

• TBD

 

 

Zájemcům o PGS doporučujeme kontaktovat příslušné školitele s předstihem.