Publications
2023
Karolová J, Kazantsev D, Svatoň M, Tušková L, Forsterová K, Maláriková D, Benešová K, Heizer T, Dolníková A, Klánová M, Winkovska L, Svobodová K, Hojný J, Krkavcová E, Froňková E, Zemanová Z, Trněný M, Klener P: Sequencing-based analysis of clonal evolution of 25 mantle cell lymphoma patients at diagnosis and after failure of standard immunochemotherapy. Am J Hematol. 2023 Oct;98(10):1627-1636. doi: 10.1002/ajh.27044. Epub 2023 Aug 21.
2022
Minařík L, Pimková K, Kokavec J, Schaffartziková A, Vellieux F, Kulvait V, Daumová L, Dusilková N, Jonášová A, Vargová KS, Králová Viziová P, Sedláček R, Zemanová Z, Stopka T.:Analysis of 5-Azacytidine Resistance Models Reveals a Set of Targetable Pathways. Cells. 2022 Jan 11;11(2):223. doi: 10.3390/cells11020223.
Stopka T, Minařík L, Dusilková N, Pešta M, Kulvait V, Špaček M, Zemanová Z, Kalousová M, Jonášová A.: G-CSF plus azacitidine versus azacitidine alone for patients with high-risk myelodysplastic syndrome: academic, open label, randomized trial. Blood Cancer J. 2022 Jul 7;12(7):105. doi: 10.1038/s41408-022-00698-2.
2021
Kozyra EJ, Göhring G, Hickstein DD, Calvo KR, DiNardo CD, Dworzak M, de Haas V, Starý J, Hasle H, Shimamura A, Fleming MD, Inaba H, Lewis S, Hsu AP, Holland SM, Arnold DE, Mecucci C, Keel SB, Bertuch AA, Tawana K, Barzilai S, Hirabayashi S, Onozawa M, Lei S, Alaiz H, Andrikovics H, Betts D, Beverloo BH, Buechner J, Čermák M, Cervera J, Haus O, Jahnukainen K, Manola KN, Nebral K, Pasquali F, Tchinda J, Turkiewicz D, Van Roy N, Zemanova Z, Pastor VB, Strahm B, Noellke P, Niemeyer CM, Schlegelberger B, Yoshimi A, Wlodarski MW: Association of unbalanced translocation der(1;7) with germline GATA2 mutations. Blood. 2021 Dec 9;138(23):2441-2445. doi: 10.1182/blood.2021012781.
Balaziova E, Vymola P, Hrabal P, Mateu R, Zubal M, Tomas R, Netuka D, Kramar F, Zemanova Z, Svobodova K, Brabec M, Sedo A, Busek P: Fibroblast Activation Protein Expressing Mesenchymal Cells Promote Glioblastoma Angiogenesis. Cancers (Basel). 2021 Jul 1;13(13):3304. doi: 10.3390/cancers13133304.
2020
Malarikova D, Berkova A, Obr A, Blahovcova P, Svaton M, Forsterova K, Kriegova E, Prihodova E, Pavlistova L, Petrackova A, Zemanova Z, Trneny M, Klener P: Concurrent TP53 and CDKN2A Gene Aberrations in Newly Diagnosed Mantle Cell Lymphoma Correlate with Chemoresistance and Call for Innovative Upfront Therapy. Cancers 2020, 12, 2120; doi:10.3390/cancers12082120.
Obr A, Klener P, Furst T, Kriegova E, Zemanova Z, Urbankova H, Jirkuvova A, Petrackova A, Malarikova D, Forsterova K, Cudova B, Sedlarikova L, Berkova A, Kasalova N, Papajik T, Trneny M: A high TP53 mutation burden is a strong predictor of primary refraktory mantle cell lymphoma. Br J Haematol. 2020. doi: 10.1111/bjh.17063. Online ahead of print.
Svobodova K, Lhotska H, Hodanova L, Pavlistova L, Vesela D, Belickova M, Vesela J, Brezinova J, Sarova I, Izakova S, Lizcova L, Siskova M, Jonasova A, Cermak L, Michalova K, Zemanova Z: Cryptic aberrations may allow more accurate prognostic classification of patients with myelodysplastic syndromes and clonal evolution. Genes Chromosomes Cancer. 2020;59:396–405. https://doi.org/10.1002/gcc.22841
Letter to the editors:
Sramkova L, Cermakova J, Kutkova K, Zemanova Z, Pavlicek P, Zuna J, Stary J, Zaliova M: Rapidly progressing acute myeloid leukemia with KAT6A-LEUTX fusion in a newborn. Pediatr Blood Cancer. 2020 Oct;67(10):e28663. doi: 10.1002/pbc.28663.
Rack KA, van den Berg E, Haferlach C, Beverloo HB, Costa D, Espinet B, Foot N, Jeffries S, Martin K, O'Connor S, Schoumans J, Talley P, Telford N, Stioui S, Zemanova Z, Hastings RJ. European recommendations and quality assurance for cytogenomic analysis of haematological neoplasms: reponse to the comments from the Francophone Group of Hematological Cytogenetics (GFCH). Leukemia. 2020 Aug;34(8):2262-2264. doi: 10.1038/s41375-020-0736-x.
2019
Zemanová Z, Michalová K, Březinová J. Implication of cytogenetic and molecular cytogenetic analysis in diagnosis of hematological malignancies in the era of the new sequencing techniques. Cas Lek Cesk. 2019 Spring;158(1):22-27.
Prukova D, Andera L, Nahacka Z, Karolova J, Svaton M, Klanova M, Havranek O, Soukup J, Svobodova K, Zemanova Z, Tuskova D, Pokorna E, Helman K, Forsterova K, Pacheco-Blanco M, Vockova P, Berkova A, Fronkova E, Trneny M, Klener P. Co-targeting of BCL2 with venetoclax and MCL1 with S63845 is synthetically lethal in vivo in relapsed mantle cell lymphoma. Clin Cancer Res. 2019;25(14):4455-4465. pii: clincanres.3275.2018. doi: 10.1158/1078-0432.CCR-18-3275.
Brezinova J, Sarova I, Svobodova K, Lhotska H, Ransdorfova S, Izakova S, Pavlistova L, Lizcova L, Skipalova K, Hodanova L, Markova J, Zemanova Z, Cermak J, Jonasova A, Michalova K. ASXL1 gene alterations in patients with isolated 20q deletion. Neoplasma. 2019 Mar 10;2019. pii: 181010N754. doi: 10.4149/neo_2018_181010N754.
Rack KA, van den Berg E, Haferlach C, Beverloo HB, Costa D, Espinet B, Foot N, Jeffries S, Martin K, O'Connor S, Schoumans J, Talley P, Telford N, Stioui S, Zemanova Z, Hastings RJ. European recommendations and quality assurance for cytogenomic analysis of haematological neoplasms. Leukemia. 2019 33(8):1851-67. doi: 10.1038/s41375-019-0378-z.
Meyer C., Lopes B., Caye-Eude A., Cave H., Arfeuille Ch., Cuccuini W., Sutton R., Venn N.C., Oh S.H., Tsaur G., Escherich G., Feuchtinger T., Kosasih H.J., Khaw S.L., Ekert P.G., Pombo de Oliveira M.S., Bidet A., Djahanschiri B., Ebersberger I., Žaliová M., Zuna J., Zemanová Z., Juvonen V., Gruemayer R.P., Fazia G., Cazzaniga G., Larghero P., Emerenciano M., Marschalek R.: Human MLL/KMT2A gene exhibits a second brakpoint cluster region for recurrent MLL-USP2 fusions. Leukemia. 2019 33(9):2306-2310.doi: 10.1038/s41375-019-0451-7.
Formankova R, Kanderova V, Rackova M, Svaton M, Brdicka T, Riha P, Keslova P, Mejstrikova E, Zaliova M, Freiberger T, Grombirikova H, Zemanova Z, Vlkova M, Fencl F, Copova I, Bronsky J, Jabandziev P, Sedlacek P, Soukalova J, Zapletal O, Stary J, Trka J, Kalina T, Skvarova K., Hlavackova E, Litzman J, Fronkova E.: Novel SAMD9 mutation in a patient with immunodefficiency, neutropenia, impaired anti-CMV response, and severe gastrointestinal involvement. Frontiers in Immunology.2019(10). nestránkováno, doi:10.3389/fimmu.2019.02194.
Minarik L, Zemanova Z, Kulvait V, Dluhosova M, Jonasova A, Stopka T: Azacitidine Switch to Lenalidomide Eradicated the TP53/CDKN2A Co-Mutated Clone and Induced Long-Term Erythroid Response in Del(5q) MDS. Ann Hematol Oncol. 2019;6(1):0000.
2018
Lemež P, Gáliková J, Michalová K, Fuchs O, MacWhannell A, Zemanová Z, Březinová J, Černá M, Stejskal J: De Novo Acute Myeloid Leukemia Involving only Granulocyte-Macrophage Line in Octogenarians with Leucocytes over 15 × 109 /L Exhibit a Favorable Response to Standard-Dose Induction Chemotherapy. Ann Hematol Oncol. 2018; 5(7):1216.
Slamova Z, Nazaryan-Petersen L, Mehrjouy MM, Drabova J, Hncarova M, Marikova T, Novotna D, Vlckova M, Vlckova Z, Bak M, Zemanova Z, Tommerup N, Sedlacek Z. Very short DNA segments can be detected and handled by the repair machinery during germline chromothriptic chromosome reassembly. Human Mutation. 2018;39:709–716. https://doi.org/10.1002/humu.2340
Jonasova A, Neuwirtova R, Polackova H, Siskova M, Stopka T, Cmunt E, Belickova M, Moudra A, Minarik L, Fuchs O, Michalova K, Zemanova Z. Lenalidomide treatment in lower risk myelodysplastic syndromes-The experience of a Czech hematology center. (Positive effect of erythropoietin ± prednisone addition to lenalidomide in refractory or relapsed patients). Leuk Res. 2018 Mar 27;69:12-17. doi: 10.1016/j.leukres.2018.03.015.
Sarova I, Brezinova J, Zemanova Z, Ransdorfova S, Svobodova K, Izakova S, Pavlistova L, Lizcova L, Berkova A, Skipalova K, Hodanova L, Salek C, Jonasova A, Michalova K. High frequency of dicentric chromosomes detected by multi-centromeric FISH in patients with acute myeloid leukemia and complex karyotype. Leuk Res. 2018 May;68:85-89. doi: 10.1016/j.leukres.2018.03.009. Epub 2018 Mar 19.
Hrusak O, De Haas V, Stancikova J, Vakrmanova B, Janotova I, Mejstrikova E, Capek V, Trka J, Zaliova M, Luks A, Bleckman K, Möricke A, Irving J, Konatkowska B, Alexander TB, Inaba H, Schmiegelow K, Stokley S, Zemanova Z, Moorman AV, Rossi JG, Felice MS, Dalla-Pozza L, Morales J, Dworzak M, Buldini B, Basso G, Campbell M, Cabrera ME, Marinov N, Elitzur S, Izraeli S, Luria D, Feuerstein T, Kolenova A, Svec P, Kreminska O, Rabin KR, Polychronopoulou S, da Costa E, Marquart HV, Kattamis A, Ratei R, Reinhardt D, Choi JK, Schrappe M, Stary J: International cooperative study indentifies treatment strategy in childhood ambiguous lineage leukemia. Blood. 2018 May 2. pii: blood-2017-12-821363.doi: 10.1182/blood-2017-12-1363 [Epub ahead of print].
Neuwirtová R., Zemanová Z., Beličková M., Březinová J., Dvořák P., Oltová A., Čermák J., Červinek L., Vozobulová V., Mašková Z., Ullrychová J., Polonyová E., Šišková M., Smělíková Y., Svoboda M., Šťastná Marková M., Michalová K., Jonášová A.: Význam cytogeneticky nepříbuzných buněčných klonů s izolovanou del(5q) a se samostatnou trizomií 8 u nemocných s MDS. Myelodysplastic syndrome News. 2018 Květen 6(1);11-18.
2017
Polgarova K, Vargova K, Kulvait V, Dusilkova N, Minarik L, Zemanova Z, Pesta M, Jonasova A, Stopka T. Somatic mutation dynamics in MDS patients treated with azacitidine indicate clonal selection in patients-responders. Oncotarget. 2017 Dec 6;8(67):111966-111978. doi: 10.18632/oncotarget.22957. eCollection 2017 Dec 19.
Vargova K, Pesta M, Obrtlikova P, Dusilkova N, Minarik L, Vargova J, Berkova A, Zemanova Z, Michalova K, Spacek M, Trneny M, Stopka T.: MiR-155/miR-150 network regulates progression through the disease phases of chronic lymphocytic leukemia. Blood Cancer J. 2017 Jul 21;7(7):e585. doi: 10.1038/bcj.2017.63
Valka J, Vesela J, Votavova H, Dostalova-Merkerova M, Horakova Z, Campr V, Brezinova J, Zemanova Z, Jonasova A, Cermak J, Belickova M.: Differential expression of homologous recombination DNA repair genes in the early and advanced stages of myelodysplastic syndrome. Eur J Haematol. 2017 Oct;99(4):323-331. doi: 10.1111/ejh.12920.
Březinová J., Šárová I., Ransdorfová Š., Zemanová Z., Michalová K.: Využití molekulárně cytogenetických technik při analýze chromozomových aberací u hematologických malignit. Přijato do časopisu Transfuze Hematol. dnes, 23, 2017, suplement 1, p. 0–00.
M Rasche, C von Neuhoff, M Dworzak, J-P Bourquin, J Bradtke, G Göhring, G Escherich, G Fleischhack, N Graf, B Gruhn, OA Haas, T Klingebiel, B Kremens, T Lehrnbecher, A von Stackelberg, J Tchinda, Z Zemanova, C Thiede, N von Neuhoff, M Zimmermann, U Creutzig, D Reinhardt: Genotype-outcome correlations in pediatric AML: the impact of a monosomal karyotype in trial AML-BFM 2004. Leukemia (2017);1–8.
O Zimmermannova, M Zaliova, AV Moorman, H Al-Shehhi, E Fronkova, Z Zemanova, T Kalina, A Vora, J Stary, J Trka, O Hrusak, J Zuna: Acute lymphoblastic leukemia with aleukemic prodrome: preleukemic dynamics and possible mechanisms of immunosurveillance. Haematologica 2017;102:e227.
2016
Svobodova K, Zemanova Z, Lhotska H, Novakova M, Podskalska L, Belickova M, Brezinova J, Sarova I, Izakova S, Lizcova L, Berkova A, Siskova M, Jonasova A, Cermak J, Michalova K: Copy number neutral loss of heterozygosity at 17p and homozygous mutations of TP53 are associated with complex chromosomal aberrations in patients newly diagnosed with myelodysplastic syndromes. Leuk Res. 2016 Mar;42:7-12. doi: 10.1016/j.leukres.2016.01.009.
Sarova I, Brezinova J, Zemanova Z, Ransdorfova S, Izakova S, Svobodova K, Pavlistova L, Berkova A, Cermak J, Jonasova A, Siskova M, Michalova K: Molecular cytogenetic analysis of dicentric chromosomes in acute myeloid leukemia. Leuk Res. 2016 Apr;43:51-7. doi: 10.1016/j.leukres.2016.01.001.
Pavlistova L., Izakova S., Zemanova Z., Bartuskova L., Langova M., Malikova P., Michalova K.: Rare congenital chromosomal aberration dic(X;Y)(p22.33;p11.32) in a patient with primary myelofibrosis. Mol Cytogenet. 2016. Aug 31;9(1):67.doi:10.1186/s13039-016-0276-2.
Svojgr K, Sumerauer D, Puchmajerova A, Vicha A, Hrusak O, Michalova K, Malis J, Smisek P, Kyncl M, Novotna D, Machackova E, Jencik J, Pycha K, Vaculik M, Kodet R, Stary J: Fanconi anemia with biallelic FANCD1/BRCA2 mutations - Case report of a family with three affected children. Eur J Med Genet. 2016 Mar;59(3):152-7. doi: 10.1016/j.ejmg.2015.11.013.
Belickova M, Vesela J, Jonasova A, Pejsova B, Votavova H, Merkerova MD, Zemanova Z, Brezinova J, Mikulenkova D, Lauermannova M, Valka J, Michalova K, Neuwirtova R, Cermak J: TP53 mutation variant allele frequency is a potential predictor for clinical outcome of patients with lower-risk myelodysplastic syndromes. Oncotarget. 2016 May 6. doi: 10.18632/oncotarget.9200. IF 6.359
Nováková M, Žaliová M, Suková M, Wlodarski M, Janda A, Froňková E, Campr V, Lejhancová K, Zapletal O, Pospíšilová D, Černá Z, Kuhn T, Švec P, Pelková V, Zemanová Z, Kerndrup G, van den Heuvel-Eibrink M, van der Velden V, Niemeyer C, Kalina T, Trka J, Starý J, Hrušák O, Mejstříková E: Loss of B cells and their precursors is the most constant feature of GATA-2 deficiency in childhood myelodysplastic syndrome. Haematologica. 2016 Jun;101(6):707-16. doi: 10.3324/haematol.2015.137711.
2015
Svobodová K, Zemanová Z, Lhotská H, Nováková M, Březinová J, Beličková M, Berková A, Šárová I, Lizcová L, Izáková S, Jonášová A, Čermák J, Michalová K: Získaná uniparentální disomie v buňkách kostní dřeně nemocných s myelodysplastickými syndromy a komplexním karyotypem. Transfuze Hematol.2015(21) 3:126-134.
Lhotska H, Zemanova Z, Cechova H, Ransdorfova S, Lizcova L, Kramar F, Krejcik Z,Svobodova K, Bystricka D, Hrabal P, Dohnalova A, Michalova K: Genetic and epigenetic characterization of low-grade gliomas revealing frequent methylation of MLH3 gene. Genes Chromosomes Cancer. 2015 Nov;54(11):655-67.
Hastings RJ, Bown N, Tibiletti MG, Debiec-Rychter M, Vanni R, Espinet B, van Roy N, Roberts P, van den Berg-de-Ruiter E, Bernheim A, Schoumans J, Chatters S, Zemanova Z, Stevens-Kroef M, Simons A, Heim S, Salido M, Ylstra B, Betts DR. Guidelines for cytogenetic investigations in tumours. Eur J Hum Genet. 2015 Mar 25. doi: 10.1038/ejhg.2015.35.
Krejčík Z, Beličková M, Hruštincová A, Kléma J, Zemanová Z, Michalová K, Čermák J, Jonášová A, Dostálová Merkerová M. Aberrant expression of the microRNA cluster in 14q32 is associated with del(5q) myelodysplastic syndrome and lenalidomide treatment. Cancer Genet. 2015 Apr;208(4):156-61.
Merkerova MD, Krejcik Z, Belickova M, Hrustincova A, Klema J, Stara E, Zemanova Z, Michalova K, Cermak J, Jonasova A.: Genome-wide miRNA profiling in myelodysplastic syndrome with del(5q) treated with lenalidomide. Eur J Haematol. 2015 Jul;95(1):35-43.
Šárová I, Březinová J, Zemanová Z, Ransdorfová Š, Izáková S, Svobodová K, Pavlištová L, Berková A, Čermák J, Jonášová A, Šišková M, Michalová K.: Molecular cytogenetic analysis of dicentric chromosomes in acute myeloid leukemia. Leuk Res. 2016 Jan 8. pii: S0145-2126(16)30001-7. doi: 10.1016/j.leukres.2016.01.001
Vyhlídalová I, Uherková L, Pleschnerová M, Špička I, Březinová J, Michalová K, Čermáková K, Polanská V, Jedelský PL, Hamšíková E, Kuželová K, Stöckbauer P. Characterization of a new human plasma cell leukemia cell line UHKT-944. Eur J Haematol. 2015 Oct;95(4):352-60. doi: 10.1111/ejh.12505.
Svojgr K, Sumerauer D, Puchmajerova A, Vicha A, Hrusak O, Michalova K, Malis J, Smisek P, Kyncl M, Novotna D, Machackova E, Jencik J, Pycha K, Vaculik M, Kodet R, Stary J.: Fanconi anemia with biallelic FANCD1/BRCA2 mutations - Case report of a family with three affected children. Eur J Med Genet. 2015 Dec 2. pii: S1769-7212(15)30051-3. doi: 10.1016/j.ejmg.2015.11.013.
Neroldova M, Frankova S, Stranecky V, Honsova E, Luksan O, Benes M, Michalova K, Kmoch S, Jirsa M: Hereditary haemochromatosis caused by homozygot HJV mutation evolved through paternal disomy. Clin Genet 2015;87:96–98.
2014
Zemanova Z, Michalova K, Buryova H, Brezinova J, Kostylkova K, Bystricka D, Novakova M, Sarova I, Izakova S, Lizcova L, Ransdorfova S, Krejcik Z, Dostalova Merkerova M, Dohnalova A, Siskova M, Jonasova A, Neuwirtova R, Cermak J: Involvement of deleted chromosome 5 in complex chromosomal aberrations in newly diagnosed myelodysplastic syndromes (MDS) is correlated with extremely adverse prognosis. Leukemia Research 2014;38:537-544.
Lhotská H, Zemanová Z, Kramář F, Lizcová L, Svobodová K, Ransdorfová Š, Bystřická D, Krejčík Z, Hrabal P, Dohnalova A, Kaiser M, Michalová K: Molekulárně cytogenetická analýza chromosomových aberací v buňkách nízkostupňových gliomů a její přínos pro klasifikaci nádoru. Klin Onkol. 2014;27(3):183-91.
Lizcova L, Zemanova Z, Lhotska H, Zuna J, Hovorkova L, Mejstrikova E, Malinova E, Rabasova J, Raska I, Sramkova L, Stary J, Michalova K: An unusual case of high hyperdiploid childhood ALL with cryptic BCR/ABL1 rearrangement. Mol Cytogenet 2014;7(1):72
Pavlistova L, Zemanova Z, Sarova I, Lhotska H, Berkova A, Spicka I, Michalova K: Change in ploidy status from hyperdiploid to near-tetraploid in multiple myeloma associated with bortezomib/lenalidomide resistance. Cancer Genet. 2014;207(7-8):326-31.
Brezinova J, Sarova I, Buryova H, Markova J, Ransdorfova S, Izakova S, Kostylkova K, Soukupova J, Zemanova Z, Michalova K: Fusion of the additional sex combs like 1 and teashirt zinc finger homeobox 2 genes resulting from ider(20q) aberration in a patient with myelodysplastic syndrome. Br J Haematol. 2014 Jan;164(1):153-5.
2013
Sarova I, Brezinova J, Zemanova Z, Bystricka D, Krejcik Z, Soukup P, Vydra J, Cermak J, Jonasova A, Michalova K. Characterization of chromosome 11 breakpoints and the areas of deletion and amplification in patients with newly diagnosed acute myeloid leukemia. Genes Chromosomes Cancer. 2013 Jul;52(7):619-35. doi: 10.1002/gcc.22058. Epub 2013 Apr 12.
Sarova I, Brezinova J, Zemanova Z, Bystricka D, Krejcik Z, Soukup P, Vydra J, Cermak J, Jonasova A, Michalova K. Characterization of chromosome 11 breakpoints and the areas of deletion and amplification in patients with newly diagnosed acute myeloid leukemia. Genes Chromosomes Cancer. 2013 Jul;52(7):619-35. doi: 10.1002/gcc.22058. Epub 2013 Apr 12.
Klamová H, Poláková KM, Mužík J, Ráčil Z, Záčková D, Steinerová K, Karas M, Faber E, Demečková E, Michalovičová-Sninská Z, Voglová J, Demitrovičová L, Mikušková E, Tóthová E, Chudej J, Markuljak I, Cmunt E, Moravcová J, Dvořáková D, Michalová K, Jarošová M, Sťastná MM, Cetkovský P, Dušek L, Koza V, Trněný M, Indrák K. Evaluation of 5-year imatinib treatment of 458 patients with CP-CML in routine clinical practice and prognostic impact of different BCR-ABL cutoff levels. Cancer Med. 2013 Apr;2(2):216-25. doi: 10.1002/cam4.59. Epub 2013 Feb 21.
Neuwirtova R, Fuchs O, Holicka M, Vostry M, Kostecka A, Hajkova H, Jonasova A, Cermak J, Cmejla R, Pospisilova D, Belickova M, Siskova M, Hochova I, Vondrakova J, Sponerova D, Kadlckova E, Novakova L, Brezinova J, Michalova K. Transcription factors Fli1 and EKLF in the differentiation of megakaryocytic and erythroid progenitor in 5q- syndrome and in Diamond-Blackfan anemia. Ann Hematol. 2013 Jan;92(1):11-8. doi: 10.1007/s00277-012-1568-1. Epub 2012 Sep 11.
Janda A, Mejstříková E, Salzer U, Grimová J, Svobodová T, Suková M, Nováková M, Hubáček P, Zemanová Z, Čermák J, Černá Z, Vítek A, Šedivá A, Hrušák O, Starý J. Deficit of GATA-2 transcription factor: New immunodeficiency syndrome with broad phenotype. First patients diagnosed in the Czech Republic and review of the literature. [Deficit transkripčního faktoru GATA-2: nová imunodeficience se širokým fenotypovým spektrem. První pacienti diagnostikovaní v České republice a přehled literatury]. Cesko-Slovenska Pediatrie 2013;68(2):101-112.
Sramkova L, Sterba J, Hrstkova H, Mihal V, Blazek B, Timr P, Cerna Z, Prochazkova, D, Hak, J, Sedlacek P, Janotova I, Vodickova E, Zemanova Z, Jarosova M, Oltova A, Zdrahalova K, Hrusak O, Mejstrikova E, Schwarz J, Zuna J, Trka J, Stary J. Development of treatment and clinical results in childhood acute myeloid leukemia in the Czech Republic. MEMO – Magazine of European Medical Oncology 2013;6(1):41-45.
Dvorak P, Lysak D, Vokurka S, Michalova K, Sarova I, Jonasova A, Hruba M, Rykovska A, Subrt I. The translocation t(2;11)(p21;q23) without MLL gene rearrangement—a possible marker of good prognosis in myelodysplastic syndrome patients. Hematol Oncol 2013. DOI: 10.1002/hon.2089
Slamova L, Starkova J, Fronkova E, Zaliova M, Reznickova L, van Delft FW, Vodickova E, Volejnikova J, Zemanova Z, Polgarova K, Cario G, Figueroa M, Kalina T, Fiser K, Bourquin JP, Bornhauser B, Dworzak M, Zuna J, Trka J, Stary J, Hrusak O, Mejstrikova E. CD2-positive B-cell precursor acute lymphoblastic leukemia with an early switch to the monocytic lineage. Leukemia 2013, DOI: 10.1038/leu.2013.354
Michalova K. Cytogenetika. Kapitola v monografii Laboratorní diagnostika – Třetí, doplněné a přepracované vydání. Tomáš Zima (ed); Galén, Praha 2013.
Year 2012
Merkerova Dostalova M, Bystricka D, Belickova M, Krejcik Z,Zemanova Z, Polak J, Hajkova H, Brezinova J, Michalova K,Cermak J: From cryptic chromosomal lesions to pathologically relevant genes: Integration of SNP-array with gene expression profiling in myelodysplastic syndrome with normal karyotype. GENES CHROMOSOMES & CANCER 2012;51(5):419-428 DOI: 10.1002/gcc.21927 Published: MAY 2012 IF11 3.306
Vlckova M, Trkova M, Zemanova Z, Hancarova M, Novotna D, Raskova D, Puchmajerova A, Drabova J, Zmitkova Z, Tan Y, Sedlacek Z.: Mechanism and Genotype-Phenotype Correlation of Two Proximal 6q Deletions Characterized Using mBAND, FISH, Array CGH, and DNA Sequencing. CYTOGENETIC AND GENOME RESEARCH 2012;136(1):15-20. DOI: 10.1159/000334709 Published: 2012 IF11 1.533
Brezinova J, Zemanova Z, Bystricka D, Sarova I, Lizcova L, Malinova E, Izákova S, Sajdova J, Sponerova D, Jonasova A, Cermak J, Michalova K: Deletion of the long arm but not the 5q31 region of chromosome 5 in myeloid malignancies. LEUKEMIA RESEARCH 2012;36(3):E43-E45 DOI: 10.1016/j.leukres.2011.11.007 Published: MAR 2012 IF11 2.923
Procházka P, Libra A, Zemanová Z, Hřebačková J, Poljaková J, Hraběta J, Bunček M, Stiborová M, Eckschlager T: Mechanisms of ellipticine-mediated resistance in UKF-NB-4 neuroblastoma cells. CANCER SCIENCE 2012;103(2): 334-341 DOI: 10.1111/j.1349-7006.2011.02137.x Published: FEB 2012 IF11 3.325
Nemec P, Zemanova Z, Kuglik P, Michalova K, Tajtlova J, Kaisarova P, Oltova A, Filkova H, Holzerova M, Balcarkova J, Jarosova M, Rabasova J, Hruba M, Spicka I, Gregora E, Adam Z, Scudla V, Maisnar V, Schutzova M, Hajek R: Complex karyotype and translocation t(4;14) define patients with high-risk newly diagnosed multiple myeloma: results of CMG2002 trial. LEUKEMIA & LYMPHOMA 2012;53(5):920-927 DOI: 10.3109/10428194.2011.634042 Published: MAY 2012 IF11 2.580
Ross F, Avet-Loiseau H, Ameye G, Gutierrez NC, Liebisch P, O'Connor SJ, Dalva K, Fabris S, Testi A, Jarosova M, Collin A, Kerndrup G, Kuglik P, Ladon D, Bernasconi P, Maes B, Zemanova Z, Michalova K, Michaux L, Neben K, Hermansen NE, Rack K, Rocci A, Protheroe R, Chiecchio L, Poirel HA, Sonneveld P, Nyegaard M, and Johnsen HE. Report from the european myeloma network on interphase FISH in multiple myeloma and related disorders. Haematologica. 2012 Aug;97(8):1272-7. doi:10.3324/haematol.2011.056176. IF11 6.424
Belickova M, Cermak J, Dostalova Merkerova M, Vesela J, Krejcik Z, Cechova E, Zemanova Z, Michalova K, Votavova H, Caniga M, Neuwirtova R, Jonasova A: Changes Associated With Lenalidomide Treatment in the Gene Expression Profiles of Patients with del(5q). Clin Lymphoma Myeloma Leuk. 2012;12(5):375-83. DOI:10.1016/j.bbr.2011.03.031
Bystricka D,Sarova I, Zemanova Z, Brezinova J,Lizcova L,Izakova S,Merkerova MD,Krejcik Z, Siskova M, Jonasova A,Neuwirtova R, Cerna O, Cermak J,Michalova K: Recurrent chromosomal breakpoints in patients with myelodysplastic syndromes and complex karyotype versus fragile sites. Leukemia Res 2012;36(6):e125-e127 DOI: 10.1016/j.leukres.2012.02.006 Published: JUN 2012 IF11 2.923
Jonasova A, Cermak J, Vondrakova J, Siskova M, Hochova I, Kadlckova E, Cerna O, Sykora M, Vozobulova V, Seifertova N, Michalova K, Zemanova Z, Brezinova J, Belohlavkova P, Kostecka A, Neuwirtova R: Thrombocytopenia at diagnosis as an important negative prognostic marker in isolated 5q- MDS (IPSS low and intermediate-1). Leuk Res. 2012 Dec;36(12):e222-4. doi: 10.1016/j.leukres.2012.08.002. IF11 2.923
Neuwirtova R, Fuchs O, Holicka M, Vostry M, Kostecka A, Hajkova H, Jonasova A, Cermak J, Cmejla R, Pospisilova D, Belickova M, Siskova M, Hochova I, Vondrakova J, Sponerova D, Kadlckova E, Novakova L, Brezinova J, Michalova K: Transcription factors Fli1 and EKLF in the differentiation of megakaryocytic and erythroid progenitor in 5q- syndrome and in Diamond-Blackfan anemia. Ann Hematol. 2012 Sep 11. [Epub ahead of print]
Hajkova H, Markova J, Haskovec C, Sarova I, Fuchs O, Kostecka A, Cetkovsky P, Michalova K, Schwarz J: Decreased DNA methylation in acute myeloid leukemia patients with DNMT3A mutations and prognostic implications of DNA methylation. Leuk Res. 2012 Sep;36(9):1128-33. Epub 2012 Jun 28. IF11 2.923
Markova J, Michkova P, Burckova K, Brezinova J, Michalova K, Dohnalova A, Maaloufova JS, Soukup P, Vitek A, Cetkovsky P, Schwarz J: Prognostic impact of DNMT3A mutations in patients with intermediate cytogenetic risk profile acute myeloid leukemia. Eur J Haematol. 2012 Feb;88(2):128-35. doi: 10.1111/j.1600-0609.2011.01716.x. Epub 2011 Nov 17. IF11 2.614
Year 2011
Zuna J, Madzo J, Krejci O, Zemanova Z, Kalinova M, Muzikova K, Zapotocky M, Starkova J, Hrusak O, Horak J, Trka J. ETV6/RUNX1 (TEL/AML1) is a frequent prenatal first hit in childhood leukaemia. Blood. 2011 Jan 6;117(1):186-9.IF10 10.558
Šárová I, Březinová J, Zemanová Z, Gančarčíková M, Vydra J, Čermák J, Michalová K: A novel gene LRP5 on 11q13.2 is rearranged in two patients with acute myeloid leukemia. Leukemia Res 2011;35(11), Nov 2011:e200-e202 IF10 2.555
Balgobind BV, Hollink IH, Arentsen-Peters ST, Zimmermann M, Harbott J, Beverloo HB, von Bergh AR, Cloos J, Kaspers GJ, de Haas V, Zemanova Z, Stary J, Cayuela JM, Baruchel A, Creutzig U, Reinhardt D, Pieters R, Zwaan CM, van den Heuvel-Eibrink MM. Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia. Haematologica. 2011 Oct;96(10):1478-87. Epub 2011 Jul 26. IF10 6.532
Lizcova L, Zemanova Z, MalinovaE, Smisek P, Stary J, Michalova K: Jumping translocations in bone marrow cells of pediatric patients with hematologic malignancies: a rare cytogenetic phenomenon. Cancer Genet. 2011 Jun;204(6):348-9. IF10 1.551
Lemež P, Klamová H, Zemanová Z, Marinov I, Fuchs O, Schwarz J, Březinová J, Provazníková D, Kostečka A, Marková J, MichalováK, Jelínek J: Unusually long survival of 67-year-old patient with near-tetraploid acute myeloid leukemia M0 without erythroblastic and megakaryocytic dysplasia. Acta Haematol. 2011;126(3):129-34. Epub 2011 Jun 24. IF 1.316
S Merjava, E Malinova,P Liskova, M Filipec, Z Zemanova, K Michalova,K Jirsova:Recurrence of posterior polymorphous corneal dystrophy is caused by the overgrowth of the original diseased host endothelium. Histochem Cell Biol. 2011 Jul;136(1):93-101. Epub 2011 Jun 22. IF10 4.727
Coenen EA, Raimondi SC, Harbott J, Zimmermann M, Alonzo TA, Auvrignon A, Beverloo HB, Chang M, Creutzig U, Dworzak MN, Forestier E, Gibson B, Hasle H, Harrison CJ, Heerema NA, Kaspers GJ, Leszl A, Litvinko N, Lo Nigro L, Morimoto A, Perot C, Reinhardt D, Rubnitz JE, Smith FO, Stary J, Stasevich I, Strehl S, Taga T, Tomizawa D, Webb D, Zemanova Z, Pieters R, Zwaan CM, van den Heuvel-Eibrink MM. Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study. Blood. 2011 Jun 30;117(26):7102-11. Epub 2011 May 6. IF10 10.558
Zdráhalová K, Sedláček P, Smíšek P, Keslová P, Štěrba J, Hrstková H, Blažek B, Mihál V, Hak J, Procházková D, Černá Z, Timr P, Zemanová Z, Jarošová M, Oltová A, Schwarz J, Pospíšilová Š, Mejstříková E, Hrušák O, Zuna J, Vodičková E, Zámková A, Blatný J, Zapletal O, Vávra V, Janotová I, Starý J. Léčebná studie Relapsed AML 2001/01, 02 pro děti s relapsem akutní myeloidní leukemie nebo primárně rezistentní nemocí zlepšila jejich naději na vyléčení. Transfuze Hematol. dnes 2011;17:113-121.
Marková J, Michková P, Burčková K, Březinová J, Michalová K, Dohnalová A, Maaloufová JS, Soukup P, Vítek A, Cetkovský P, Schwarz J.: Prognostic impact of DNMT3A mutations in patients with intermediate cytogenetic risk profile acute myeloid leukemia. Eur J Haematol. 2011 Oct 4. doi: 10.1111/j.1600-0609.2011.01716.x. [Epub ahead of print] IF10 2.785.
Zackova D, Klamova H, Dusek L, Muzik J, Polakova KM, Moravcova J, Jurcek T, Dvorakova D, Racil Z, Pospisil Z, Oltova A, Michalova K, Brezinova J, Razga F, Doubek M, Cetkovsky P, Trneny M, Mayer J.: Imatinib as the first-line treatment of patients with chronic myeloid leukemia diagnosed in the chronic phase: can we compare real life data to the results from clinical trials? Am J Hematol. 2011 Mar;86(3):318-21. Epub 2011 Feb 15.IF10 3.576.
Year 2010
Göhring G, Michalova K, Beverloo HB, Betts D, Harbott J, Haas OA, Kerndrup G, Sainati L, Bergstraesser E, Hasle H, Stary J, Trebo M, van den Heuvel-Eibrink MM, Zecca M, van Wering ER, Fischer A, Noellke P, Strahm B, Locatelli F, Niemeyer CM, Schlegelberger B. Complex karyotype newly defined: the strongest prognostic factor in advanced childhood myelodysplastic syndrome. Blood. 2010 Aug 27. [Epub ahead of print] IF09 10,555
von Neuhoff C, Reinhardt D, Sander A, Zimmermann M, Bradtke J, Betts DR, Zemanova Z, Stary J, Bourquin JP, Haas OA, Dworzak MN, Creutzig U. Prognostic impact of specific chromosomal aberrations in a large group of pediatric patients with acute myeloid leukemia treated uniformly according to trial AML-BFM 98. J Clin Oncol. 2010;28(16):2682-9. IF09 17,793
Lizcova L, Zemanova Z, Malinova E, Jarosova M, Mejstrikova E, Smisek P, Pospisilova D, Stary J, Michalova K: A novel recurrent chromosomal aberration involving chromosome 7 in childhood MDS. Cancer Genet Cytogenet. 2010;201:52-56.IF09 1,537
Zuna J, Zaliova M, Muzikova K, Meyer C, Lizcova L, Zemanova Z, Brezinova J, Votava F, Marschalek R, Stary J, Trka J. Acute leukemias with ETV6/ABL1 (TEL/ABL) fusion: poor prognosis and prenatal origin. Genes Chromosomes Cancer. 2010;49(10):873-84. IF09 3,858
Mejstrikova E, Volejnikova J, Fronkova E, Zdrahalova K, Kalina T, Sterba J, Jabali Y, Mihal V, Blazek B, Cerna Z, Prochazkova D, Hak J, Zemanova Z, Jarosova M, Oltova A, Sedlacek P, Schwarz J, Zuna J, Trka J, Stary J, Hrusak O.Prognosis of children with mixed phenotype acute leukemia treated on the basis of consistent immunophenotypic criteria.Haematologica. 2010;95(6):928-35. IF09 6,416
Lemez P, Attarbaschi A, Béné MC, Bertrand Y, Castoldi G, Forestier E, Garand R, Haas OA, Kagialis-Girard S, Ludwig WD, Matutes E, Mejstríková E, Pages MP, Pickl W, Porwit A, Orfao A, Schabath R, Starý J, Strobl H, Talmant P, van't Veer MB, Zemanova Z; European Group for the Immunological Characterization of Leukemias (EGIL). Childhood near-tetraploid acute lymphoblastic leukemia: an EGIL study on 36 cases. Eur J Haematol. 2010;85(4):300-8. IF09 2,345
Šárová I, Březinová J, Zemanová Z, Izáková S, Lizcová L, Malinová E, Berková A, Čermák J, Maaloufová J, Nováková L, Michalová K: Cytogenetic manifestation of chromosome 11 duplication/amplification in acute myeloid leukemia. Cancer Genet Cytogenet. 2010;199:121-127. IF09 1,537
Brezinova J, Berkova A, Vcelikova S, Zemanova Z, Izakova S, Sarova I, Cechova H, Tajtlova J, Grosova L, Lizcova L, Malinova E, Zemanova M, Cmunt E, Karban J, Trneny M, Schwarz J, Michalova K. Telomere length, molecular cytogenetic findings, and immunophenotypic features in previously untreated patients with B-chronic lymphocytic leukemia. Neoplasma. 2010;57(3):215-21. IF09 1.192
Nemec P, Zemanova Z, Greslikova H, Michalova K, Filkova H, Tajtlova J, Kralova D, Kupska R, Smetana J, Krejci M, Pour L, Zahradova L, Sandecka V, Adam Z, Buchler T, Spicka I, Gregora E, Kuglik P, Hajek R. Gain of 1q21 is an unfavorable genetic prognostic factor for multiple myeloma patients treated with high-dose chemotherapy. Biol Blood Marrow Transplant. 2010;16(4):548-54. IF09 3.149
Dundr P, Fischerová D, Povýšil C, Berková A, Bauerová L, Cibula D. Uterine tumors with neuroectodermal differentiation. A report of 4 cases. Pathol Oncol Res. 2010;16(4):601-8. IF09 1.152
Bystřická D, Zemanová Z, Březinová J, Gančarčíková M, Grosová L, Šárová I, Izáková S, Berková A, Michalová K. Complex karyotypes evaluated by mFISH and aCGH. Folia Biol-Prague. 2010;56:223-230. IF081.140
Válková V, Schwarz J, Vítek A, Marková M, Pohlreich D, Benešová K, Michalová K, Cetkovský P, Trněný M. The effect of allogeneic stem cell transplantation on high risk chronic lymphocytic leukaemia: a single centre retrospective analysis. Hematol Oncol. 2010 Jun 10. [Epub ahead of print] IF09 1.869
Szotkowski T, Muzik J, Voglova J, Koza V, Maaloufova J, Kozak T, Jarosova M, Michalova K, Zak P, Steinerova K, Vydra J, Lanska M, Katrincsakova B, Sicova K, Pavlik T, Dusek L, Indrak K. Prognostic factors and treatment outcome in 1,516 adult patients with de novo and secondary acute myeloid leukemia in 1999-2009 in 5 hematology intensive care centers in the Czech Republic.Neoplasma. 2010;57(6):578-89. IF09 1.192
Klamova H, Faber E, Zackova D, Markova M, Voglova J, Cmunt E, Novakova L, Machova-Polakova K, Moravcova J, Dvorakova D, Michalova K, Brezinova J, Oltova A, Jarosova M, Cetkovsky P, Indrak K, Mayer J. Dasatinib in imatinib-resistant or -intolerant CML patients: data from the clinical practice of 6 hematological centers in the Czech Republic. Neoplasma. 2010;57(4):355-9. IF09 1.192
Berková A, Michalová K. Cytogenetické nálezy u chronické lymfocytární leukemie (CLL). Transfuz Hemat dnes. 2010;16:52–55.
Gancarcíková M, Zemanová Z, Brezinová J, Berková A, Vcelíková S, Smigová J, Michalová K. The role of telomeres and telomerase complex in haematological neoplasia: the length of telomeres as a marker of carcinogenesis and prognosis of disease. Prague Med Rep. 2010;111(2):91-105.
Lemez P, Gáliková J, Michalová K, Dvoráková D, MacWhannell A, Zemanová Z, Stejskal J.: Nemocní starší 80 let s de novo akutními myeloidními leukémiemi bez dysplasie v erytroblastické a/nebo megakaryocytární řadě dosahují kompletní remise a delšího přežití po klasické chemoterapii 3+7 (Patients older than 80 years with de novo acute myeloid leukemias without erythroblastic and/or megakaryocytic dysplasia achieve complete remission and longer survival after classical chemotherapy 3 + 7). Vnitr Lek. 2010 Jan;56(1):37-43.
